Hot Roast Beef Sandwiches

These hot roast beef sandwiches with cheddar cheese sauce are so easy to make! Each sandwich is layered with warm deli roast beef, creamy cheddar cheese sauce, and a touch of horseradish mayo.

a stack of sandwiches.

Say hello to my take on a particular fast food sandwich that we can make at home in about 15 minutes. 15 minutes! It’s true!

I’ve loved these hot roast beef sandwiches for a few years now. They’re super simple to make, and they satisfy that craving for something procured at a drive-through. But we get to stay home, which is always a win in my book.

Warm roast beef topped with a super creamy cheddar cheese sauce and quick horseradish mayo served on hamburger buns. Adding some curly fries on the side is not required but highly encouraged.

a bun topped with roast beef and cheddar cheese sauce.

Ingredients

  • Thinly-sliced deli roast beef: It’s so much better than what you get in a package, so treat yourself and get some of the good stuff at the deli counter.
  • Shredded cheddar cheese: I like mild cheddar, but you can use whatever good melting cheese you like. I’ve made the sauce with pepper jack cheese, and it’s delicious, too.
  • Evaporated milk: This makes the best creamy cheese sauce.
  • Cornstarch: You need a couple of teaspoons to thicken the cheese sauce.
  • Horseradish mayonnaise: I make my own, but you can buy it at the grocery store to make it easier.
  • Butter: I like to heat the roast beef with just a little bit of butter.
  • Hamburger buns

How to Make the Sandwiches

โ˜‘๏ธ Make the Horseradish Mayo

Combine the horseradish and mayonnaise in a small bowl. If you’re using store-bought, you can skip this step.

โ˜‘๏ธ Make the Cheddar Cheese Sauce

Place the shredded cheese in a microwave-safe bowl. Add the cornstarch and lightly toss the cheese so it’s evenly coated.

Add the milk and heat the ingredients in the microwave for about a minute. Stir until the sauce is smooth. If the cheese is not completely melted, you can heat it again for 20 to 30 seconds.

โ˜‘๏ธ Warm the Roast Beef

Melt the butter in a small pan over medium heat. Add the roast beef and warm it in the butter (turning it a few times) until it’s hot.

โ˜‘๏ธ Assemble the Sandwiches

Spread the mayo on the hamburger buns. Top the bottom buns with the roast beef, spoon the cheese sauce over the meat, and place the other bun on top.

a roast beef sandwich with cheddar cheese sauce.
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Hot Roast Beef Sandwiches

a roast beef sandwich with cheddar cheese sauce.

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4.6 from 8 reviews

These hot roast beef sandwiches are quick and easy, thanks to a simple cheddar cheese sauce that’s made in the microwave.

  • Author: April Anderson
  • Prep Time: 10 minutes
  • Cook Time: 5 minutes
  • Total Time: 15 minutes
  • Yield: 4 sandwiches 1x
  • Category: Dinner
  • Method: Saute
  • Cuisine: American

Ingredients

Scale
  • 1 1/2 tsp creamy horseradish
  • 1/4 cup mayonnaise
  • 1 cup shredded mild cheddar cheese (see note)
  • 2 tsp cornstarch
  • 1/2 cup evaporated milk
  • 1 tbsp butter
  • 1/2 pound thin-sliced deli roast beef
  • 4 hamburger buns

Instructions

  1. Combine the horseradish and mayonnaise in a small bowl.
  2. Place the shredded cheese in another small bowl and toss it with the cornstarch. Add the evaporated milk and heat it in the microwave for about a minute. Stir until smooth.
  3. Melt the butter in a skillet and add the roast beef. Cook it for a few minutes until it’s warmed through.
  4. Divide the horseradish mayonnaise among the buns. Top with the roast beef and cheese sauce. Serve warm.

Notes

For the best results, shred block cheddar cheese for this recipe instead of using pre-shredded cheese, which has stabilizers that can cause issues with the sauce.

Nutrition

  • Serving Size: 1 sandwich
  • Calories: 463
  • Sugar: 6.4g
  • Sodium: 755.4mg
  • Fat: 27.5g
  • Saturated Fat: 10.2g
  • Unsaturated Fat: 15.5g
  • Trans Fat: 0.3g
  • Carbohydrates: 34g
  • Fiber: 1.7g
  • Protein: 13.9g
  • Cholesterol: 57mg

Do you love this recipe? Don’t forget to leave a comment and your recipe star rating!

The nutrition is an estimate only. It was calculated using Nutrifox, an online nutrition calculator.

More Easy Comfort Food Recipes

I hope you try these roast beef sandwiches! They’re so easy and so delicious. Enjoy ๐Ÿ–ค

Happy cooking,

April

21 Comments

  1. Arbyโ€™s is one of my favorite fast food restaurants but theyโ€™re so expensive that I almost never go there. These sandwiches were so delicious that Iโ€™m already planning on making them again this week. Thanks for the recipe!

    1. Also wondering if there is a substitute for the evaporated milk? Just trying to make this with stuff I already have! Thanks again!

      1. I’ve only tried it with cornstarch and evaporated milk – I’m not sure what the consistency will be like with the substitutions, but I suspect it won’t be as creamy and the cheese might be stringy. Let me know if you try it!

  2. This is a great recipe for leftover roast beef. I sliced it quite thin and it warmed nicely in the butter/saucepan. Instead of buns, I made some fresh sliced sourdough bread that I buttered lightly and grilled. Once the bread was grilled I spread both slices with the mayo mixture, topped it with the meat and cheese. Scrumptious! I will definitely use this recipe again.






  3. These were super delicious! I heated my cheese mixture for 3 minutes, stirring a couple times. I used a glass bowl so it took longer! Very yummy recipe, we loved the horseradish mayo!






  4. Delicious! I was thinking how much i would like a beef and cheddar from Arby’s and your recipe was even better! Do you think the cheese sauce will reheat well? I have leftovers.






    1. I think the sauce should rewarm ok – you may need to add a little more milk to thin it.

  5. This was good. We did decide that it’s better without the horseradish. Probably just a personal preference.

    I loved how quick and easy it was. Especially making the cheese sauce in the microwave. Thanks for the quick dinner.






  6. I attempted to make the cheese sauce 3 times and it became a thick glob every time. I reduced the corn starch on the 2 nd attempt: same result. I used no corn starch on the 3rd attempt: same result. I used shredded mild cheddar cheese. Any thoughts?






        1. No, you didn’t miss anything – I’ve made it with pre shredded cheese before without problems, but I wonder if different brands work differently. I am updating the recipe with this info – again, I’m sorry you had issues!

  7. Oh yeah, this one’s a winner. I’ve been trying to perfect cheese sauce since I tried it with nachos, but could never get quite a cheesy enough flavour, I added some yeast flakes and that definitely did it. This sandwich is chef’s kiss, and I think I’ve found my new favourite.

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